Doxapram and idiopathic hypoventilation
نویسندگان
چکیده
منابع مشابه
Chronic hypoventilation syndromes and sleep-related hypoventilation.
Chronic hypoventilation affects patients with disorders on any level of the respiratory system. The generation of respiratory impulses can be impaired in congenital disorders, such as central congenital alveolar hypoventilation, in alterations of the brain stem or complex diseases like obesity hypoventilation. The translation of the impulses via spinal cord and nerves to the respiratory muscles...
متن کاملPanic attacks induced by doxapram.
Doxapram is a respiratory stimulant thought to act by stimulating medullary neurones and carotid oxygen receptors (Kato and Buckley 1964). It changes neither oxygen uptake nor CO2 production, but produces substantial hyperventilation (Calvedey et al 1983). Hyperventilation occurs during naturally occurring or pharmacologically induced panic attacks, and perhaps also in panic patients between at...
متن کاملInteractions between morphine and doxapram in the rabbit and mouse.
Certain actions of doxapram, administered alone and in combination with morphine, have been examined in the rabbit and the mouse. Single doses of doxapram were capable of stimulating respiration in both species. There was an increase in tidal volume in the rabbit and an increase in respiratory rate in the mouse. In both species the duration of action of single doses of doxapram was less than 15...
متن کاملChronic hypoventilation and its management.
While obstructive sleep apnoea syndrome dominates discussion of the prevalence of sleep disordered breathing, nocturnal hypoventilation remains extremely prevalent in those with chronic ventilatory disorders and in the natural history of these conditions pre-dates the development of daytime ventilatory failure. In this review the clinical management of chronic hypoventilation in neuromuscular d...
متن کاملThe obesity hypoventilation syndrome.
We only need to look around us to see that we are in an epidemic of obesity and obesity-related medical problems. The obesity hypoventilation syndrome is a disorder in which an obese person with normal lungs chronically hypoventilates. Obesity impairs ventilatory mechanics, increases the work of breathing and carbon dioxide production, results in respiratory muscle dysfunction, and reduces vent...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1984
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1984.tb06504.x